What Is Nicotine Replacement Therapy?
Nicotine replacement therapy, usually shortened to NRT, provides nicotine without exposing the user to tobacco smoke or the products created when a cigarette burns.
When you stop smoking, the reduction in nicotine can cause cravings and withdrawal symptoms. These may include irritability, anxiety, restlessness and difficulty concentrating. NRT replaces some of the nicotine previously obtained from cigarettes and may make these symptoms easier to manage.
Healthdirect describes NRT as a first-line medicine for nicotine dependence. Common options in Australia include:
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Nicotine patches
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Nicotine gum
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Nicotine lozenges
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Nicotine mouth spray
Registered nicotine patch, gum and lozenge products are included in the Australian Register of Therapeutic Goods. They are available without a prescription; however, that does not mean every format or strength suits every person.
How Do Patches, Gum and Lozenges Compare?
The main difference is how they deliver nicotine.
A patch releases nicotine gradually through the skin. Gum and lozenges deliver nicotine through the lining of the mouth and are used around particular cravings or anticipated triggers.
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Patch |
Gum |
Lozenge |
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How it works |
Steady, slow release of nicotine through the skin (transdermal). |
Nicotine absorbed through the lining of your mouth as you “chew and park”. |
Dissolves slowly in your mouth and is absorbed through the mouth lining. |
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Speed |
Steady, all-day background relief. |
Fast relief for a craving in the moment. |
Fast relief for a craving in the moment. |
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Well suited to |
Constant, background cravings; wanting a simple once-a-day option. |
Sudden, breakthrough cravings; liking something to do with your hands and mouth. |
Sudden cravings, discreetly; finding gum hard on the jaw or teeth. |
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How you use it |
Apply one to clean, dry skin each morning; move the site daily. |
“Chew and park” a piece for about 30 minutes; avoid acidic drinks just before. |
Let it dissolve slowly - don’t chew or swallow it; avoid acidic drinks just before. |
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Common side effects |
Skin irritation at the site; vivid dreams if worn overnight. |
Hiccups, jaw ache, mouth or throat irritation. |
Hiccups, mouth or throat irritation, nausea. |
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How you get it in Australia |
Over the counter; subsidised on the PBS with a prescription. |
Over the counter at brick-and-mortar and online pharmacies and many supermarkets. |
Over the counter at brick-and-mortar and online pharmacies and many supermarkets. |
General guide only, drawn from Quit.org.au and RACGP guidance. Always read the label and ask your pharmacist.
How Do Nicotine Patches Work?
A nicotine patch is applied to the skin and releases nicotine gradually over its labelled wear period.
Patches may suit people who prefer a longer-acting option that does not need to be used repeatedly during the day. They may also be considered when cravings occur regularly rather than only around particular triggers.
Patches generally come in 16-hour and 24-hour formats:
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A 16-hour patch is usually applied in the morning and removed before bed.
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A 24-hour patch is generally worn overnight and replaced the following morning.
Strengths vary between patch systems. Common 24-hour strengths include 21 mg, 14 mg and 7 mg, while some 16-hour systems use 25 mg, 15 mg and 10 mg. These examples are not a personal dosing schedule.
Possible side effects include application-site redness or itching, headaches, sleep disturbance, vivid dreams, nausea and dizziness.
For more detailed guidance, see the myduke® article about nicotine patches in Australia.
How Does Nicotine Gum Work?
Nicotine gum releases nicotine that is absorbed through the mouth lining. It is not used like ordinary chewing gum.
Australian Quit guidance recommends the park-and-chew method:
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Chew slowly until you notice a tingling sensation or stronger taste.
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Park the gum under your tongue or between your cheek and gum.
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When the sensation fades, chew slowly again.
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Repeat according to the product directions.
Chewing continuously can cause more nicotine-containing saliva to be swallowed and may contribute to hiccups, nausea or indigestion.
Nicotine gum may suit someone who prefers an option they can use around a particular craving. However, it may be less suitable for someone with dentures, dental work, jaw discomfort or difficulty chewing.
Common strengths include 2 mg and 4 mg. The appropriate strength depends on factors such as daily cigarette use and how soon after waking a person smokes.
For more detail, read the myduke® guide to using nicotine gum in Australia.
How Do Nicotine Lozenges Work?
Nicotine lozenges dissolve in the mouth, allowing nicotine to be absorbed through the lining of the mouth.
You should not usually chew them, swallow them whole, or use them like ordinary confectionery lozenges. Quit recommends the roll technique, sometimes called the cheek-to-cheek method:
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Place the lozenge between your cheek and gum.
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Move or roll it around your mouth from time to time.
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Allow it to dissolve completely, as directed on the label.
Depending on the product, this may take approximately 15 to 20 minutes.
Acidic drinks such as coffee, fruit juice and soft drinks can affect absorption. Quit advises waiting approximately 15 minutes after these drinks before using a lozenge and avoiding food or drink while it dissolves.
Lozenges may suit someone who wants a shorter-acting oral form but finds chewing gum uncomfortable. Possible side effects include hiccups, mouth or throat irritation, nausea, heartburn or indigestion.
Common strengths include 2 mg and 4 mg, but products vary. Read the label and ask a pharmacist if you are unsure which strength or frequency may be appropriate.
What Factors Can Help You Compare NRT Formats?
An article cannot determine which NRT format is right for you. The following factors can help you prepare for a conversation with a nurse practitioner, pharmacist or doctor.
When Do Your Cravings Occur?
A patch may be considered when cravings occur throughout much of the day. Gum or lozenges may be useful when cravings occur around particular routines or situations.
Craving patterns are only one consideration and should not be the sole basis for selecting treatment.
How Soon After Waking Do You Smoke?
Smoking soon after waking can indicate a higher level of nicotine dependence. This information may influence the starting strength or treatment approach a health professional discusses with you.
Would You Prefer a Longer- or Shorter-Acting Format?
Some people prefer applying a patch once each day. Others prefer an oral form they can use around anticipated triggers.
Convenience matters because treatment can only help when used as directed.
Do You Have Skin Sensitivity?
A patch may cause redness or itching at the application site. If you have a skin condition, adhesive sensitivity or a previous reaction, speak with a nurse practitioner, pharmacist or doctor before use.
Do You Have Dental or Jaw Concerns?
Gum may not be suitable for people with certain dental work, dentures or jaw discomfort. A lozenge or patch may be a better option, depending on the individual.
Do You Experience Mouth or Throat Irritation?
Both gum and lozenges can irritate the mouth or throat. Technique can affect some unwanted effects, but persistent symptoms require professional advice.
Does Sleep Disturbance Affect Your Choice?
Some people experience vivid dreams or disturbed sleep with a 24-hour patch. A 16-hour format may be discussed, but any change should follow the label and professional guidance.
Are You Pregnant, Breastfeeding or Managing a Health Condition?
Speak with a nurse practitioner, doctor or pharmacist before using NRT if you:
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Are pregnant or breastfeeding
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Have a long-term health condition
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Have recently experienced cardiovascular symptoms
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Take other medicines
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Have previously experienced problems with NRT
A healthcare professional can consider your circumstances rather than relying on a general comparison.
Can You Use a Patch With Gum or Lozenges?
Using a nicotine patch together with a shorter-acting oral form is known as combination NRT.
The patch provides gradual nicotine delivery, while gum or a lozenge can be used around particular cravings. This does not mean that everyone should combine products or that adding more nicotine is automatically appropriate.
The RACGP smoking-cessation guideline recommends a patch with an oral form of NRT, accompanied by behavioural support, for people who smoke and have evidence of nicotine dependence.
A nurse practitioner, pharmacist or doctor can help determine:
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Whether combination NRT may be appropriate
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Which products and strengths to use
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When to use each form
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How to monitor unwanted effects
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When and how treatment may be reduced
Do not combine NRT products or increase their use solely because cravings continue. Persistent cravings may indicate that a nurse practitioner, pharmacist, or doctor should review the treatment plan.
What Side Effects Should You Consider?
All medicines can cause side effects. The type of effect may differ according to the NRT format.
Nicotine Patch
Possible effects include:
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Skin redness or itching
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Headache
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Sleep disturbance
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Vivid dreams
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Nausea or dizziness
Nicotine Gum
Possible effects include:
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Hiccups
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Jaw discomfort
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Mouth or throat irritation
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Nausea
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Heartburn or indigestion
Nicotine Lozenge
Possible effects include:
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Hiccups
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Mouth or throat irritation
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Nausea
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Heartburn or indigestion
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Increased saliva
Technique can contribute to some unwanted effects, but it is not the only possible cause.
Read the label and consumer information for a complete list. Speak with a nurse practitioner, pharmacist or doctor if side effects persist, become difficult to manage or concern you. Seek urgent medical assistance if you experience a severe reaction or otherwise feel seriously unwell.
How Long Is NRT Used?
Treatment duration varies according to the product and individual circumstances. Australian Quit guidance generally recommends using patches, gum or lozenges for at least eight weeks and reducing use as directed.
Some products use staged schedules, while others have different directions. Do not assume that one duration or reduction plan applies to every form.
Speak with a nurse practitioner, pharmacist or doctor before changing, extending or combining NRT, particularly if:
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Cravings remain difficult to manage
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You continue to smoke
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You experience side effects
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You use more than the labelled amount
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You are unsure how to reduce treatment
Is NRT Available Through the PBS?
PBS access differs by NRT product and eligibility group.
Some nicotine patches may be available at a subsidised PBS price when prescribed, subject to current restrictions. Eligible Aboriginal and Torres Strait Islander people may have additional access to patches, gum and lozenges through Closing the Gap arrangements.
PBS listings and conditions can change. Ask a nurse practitioner, doctor or pharmacist about current eligibility or check the Pharmaceutical Benefits Scheme website.
NRT products are also available without a prescription through pharmacies and other permitted suppliers.
How Does Behavioural Support Fit With NRT?
NRT primarily helps with the physical symptoms of nicotine withdrawal. Behavioural support can help you identify and respond to the routines, emotions and situations connected with smoking.
Support may include:
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Planning for known triggers
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Developing alternatives to smoking
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Changing routines associated with cigarettes
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Receiving follow-up from a healthcare professional
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Speaking with a Quitline counsellor
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Asking family or friends for practical support
Quitline provides free and confidential support on 13 7848. A counsellor can help you develop a quit plan and respond to setbacks.
How Can myduke® Support a Quit Attempt?
Patches, gum and lozenges are available without a prescription, and a pharmacist can provide product-specific guidance. You don't need to complete a myduke® assessment to access these forms of NRT.
myduke® is an Australian clinical health service for adults seeking broader support with smoking cessation or nicotine dependence.
The online pathway begins with a confidential health questionnaire. An independent AHPRA-registered doctor reviews the information and determines whether prescription treatment is clinically appropriate.
Where prescription treatment is provided, it is dispensed through an authorised Australian pharmacy partner. Ongoing oversight may include treatment monitoring and step-down guidance where appropriate.
Completing an assessment does not guarantee approval, a prescription or access to a particular treatment. The questionnaire supports clinical review but does not replace the practitioner’s independent judgement.
Smoking cessation or nicotine dependency products are unapproved therapeutic goods. This means that the TGA has not evaluated them for safety, quality, or efficacy.
Frequently Asked Questions
Which NRT format may suit me?
That depends on your nicotine dependence, craving pattern, routine, health circumstances and preferences.
A patch may be considered for gradual nicotine delivery across the day. Gum or lozenges may be considered for cravings that occur at particular times. A nurse practitioner, pharmacist or doctor can help compare the formats.
Can you use a patch with gum or lozenges?
Combination NRT involves using a patch with a shorter-acting oral form. The RACGP recommends this approach, together with behavioural support, for nicotine-dependent people who smoke.
Ask a nurse practitioner, pharmacist or doctor whether combination NRT is appropriate and how to use each product.
How many cigarettes does gum or a lozenge replace?
There is no fixed cigarette-to-dose conversion. Use gum and lozenges according to their labels to help manage cravings or anticipated triggers.
The appropriate strength and frequency depend on the product, smoking pattern and individual circumstances.
How many cigarettes does a 21 mg patch replace?
A 21 mg patch does not correspond to a fixed number of cigarettes. It is a strength used in some 24-hour patch systems.
A nurse practitioner, pharmacist or doctor can consider factors such as daily cigarette use and how soon after waking you smoke when discussing a starting strength.
Which form has fewer side effects?
There is no format with universally fewer side effects. Patches commonly cause skin-related effects, while gum and lozenges can cause mouth, throat or digestive effects.
Individual experiences vary. Speak with a nurse practitioner, pharmacist or doctor if a product causes persistent or concerning symptoms.
Is nicotine gum or a lozenge faster than a patch?
Gum and lozenges are shorter-acting than patches and are used around particular cravings. Patches release nicotine gradually and are not intended to respond immediately to a sudden urge.
Are nicotine patches, gum and lozenges ARTG-registered?
ARTG includes nicotine patch, gum, and lozenge products. Check the label and Australian product information for the particular medicine you are considering.
The Bottom Line
Nicotine patches, gum and lozenges deliver nicotine in different ways. A patch provides gradual delivery during its labelled wear period, while gum and lozenges are shorter-acting options used around cravings.
No single format suits everyone. Relevant factors include nicotine dependence, craving timing, routine, skin or dental considerations, other health circumstances and personal preference.
The RACGP recommends combination NRT with behavioural support for nicotine-dependent people who smoke, but combining products still requires suitable strengths and correct use. A nurse practitioner, pharmacist or doctor can provide individual guidance.
Australian adults seeking a broader clinical assessment can also learn about myduke®’s online pathway. An independent AHPRA-registered doctor reviews the information provided and determines whether prescription treatment is clinically appropriate.
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Important information This article provides general information only and does not replace individual medical or pharmaceutical advice. Always read the label and follow the directions for use. If you’re unsure, speak with your pharmacist or doctor. myduke® is a clinical health service. Under Australian law, therapeutic vapes are unapproved goods. They are only available to patients 18+ for smoking cessation or nicotine dependence following a consultation with a pharmacist (for ≤20mg/mL) or a prescription from a medical practitioner (for >20mg/mL). Always read the label and follow practitioner advice. |